MRCGP AKT Question Bank
4,376 MRCGP Applied Knowledge Test questions across clinical medicine, evidence and admin. Try 100 free.
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About the MRCGP AKT exam
The MRCGP Applied Knowledge Test assesses the knowledge base underpinning UK general practice. MedPrep covers all three domains (clinical medicine, evidence-based practice, and health informatics/administration) with UK-guideline-referenced explanations tuned to the way the AKT tests real GP decision-making.
Who it's for
GP trainees (ST1 to ST3) preparing for the MRCGP Applied Knowledge Test.
Exam format
Around 200 items in 3h10m: single-best-answer, EMQs and data interpretation, delivered at a Pearson VUE centre.
Topics covered
Free sample MRCGP AKT questions
Try a few real questions from the bank. Pick an answer to check yourself and see the full explanation.
A 58-year-old man presents with low back pain 2 weeks post-lifting. X-ray lumbar spine: L1 vertebral compression fracture (fragility fracture - minimal trauma). History: long-term prednisolone 10 mg daily 5 years (rheumatoid arthritis), smoker 20 pack-years, alcohol 30 units/week, BMI 19 kg/m² (underweight). Investigations: calcium 2.35 mmol/L (normal 2.20-2.60 mmol/L), phosphate 1.1 mmol/L (normal 0.8-1.5 mmol/L), ALP 95 U/L (normal <120 U/L - excludes Paget's/osteomalacia), 25-OH vitamin D 35 nmol/L (insufficient - normal >50 nmol/L), testosterone 8 nmol/L (low-normal 10-30 nmol/L - hypogonadism), TSH 2.5 mU/L (normal), PTH 45 pg/mL (normal 10-65 pg/mL). DEXA scan: lumbar spine T-score -3.2 (osteoporosis - T-score <-2.5), femoral neck T-score -2.8 (osteoporosis). Clinical diagnosis: osteoporosis secondary causes (glucocorticoid-induced osteoporosis - prednisolone 10 mg daily 5 years, fragility fracture L1, male hypogonadism, underweight BMI 19, smoking, excess alcohol). What is the most appropriate management?
Select an answer to see the explanation.
A 72-year-old man with type 2 diabetes mellitus + rheumatoid arthritis (methotrexate 20 mg weekly + prednisolone 5 mg daily) presents with 24 hours acute right knee pain severe + swelling + fever 38.8°C. History: no trauma, rheumatoid arthritis well-controlled. Examination: right knee hot + swollen + effusion tense, restricted range movement (pain limitation), erythema overlying skin. Left knee/other joints normal. Investigations: WCC 18 × 10⁹/L (leukocytosis), neutrophils 15 × 10⁹/L (neutrophilia 80%), ESR 95 mm/hr, CRP 185 mg/L (markedly elevated). Knee aspirate urgent: appearance cloudy purulent, WCC 75,000 cells/µL (markedly elevated - >50,000 cells/µL diagnostic septic arthritis), neutrophils 95%, Gram stain positive cocci clusters (Gram-positive cocci - Staphylococcus aureus), culture pending. Blood cultures: 2/2 bottles positive Gram-positive cocci (bacteremia - Staphylococcus aureus). Clinical diagnosis: septic arthritis bacterial (acute monoarthritis right knee + fever + synovial fluid WCC 75,000 >50,000 cells/µL + Gram stain positive cocci + immunosuppressed diabetes/methotrexate/prednisolone, pyogenic joint infection Staphylococcus aureus). What is the most appropriate management?
Select an answer to see the explanation.
A 45-year-old man with depression on sertraline 100 mg daily is admitted with confusion, agitation, tremor, hyperreflexia, dilated pupils, and temperature 38.9°C. Symptoms started 2 days after his GP added tramadol 50 mg QDS for back pain. What is the MOST likely diagnosis?
Select an answer to see the explanation.
MRCGP AKT topic one-page PDFs
Free ward-style revision sheets for high-yield MRCGP AKT topics. Open a sheet and use Download PDF to save or print.
MRCGP AKT revision notes
Free clinician-written notes for topics tested in MRCGP AKT.
Frequently asked questions
Is MedPrep's MRCGP AKT question bank free?
You can answer 100 MRCGP AKT questions completely free, with full explanations and progress tracking, and no card is required. After that, a single affordable subscription unlocks the whole bank.
How many MRCGP AKT questions are there?
The MRCGP AKT bank has 4,376 exam-style questions, each with a structured, guideline-referenced explanation.
Are the questions up to date with UK guidelines?
Yes. Every explanation is cross-referenced against current NICE, BNF and relevant UK/European guidelines, and the bank is curated by a UK-trained, CCT-holding clinician.