Coronary syndromes, arrhythmias, valvular disease, heart failure, congenital defects, and vascular conditions — core content for MRCP, PLAB, and UKMLA.

Asthma, COPD, pneumonia, ILD, lung cancer, TB, and pleural disease with NICE-aligned investigation and management pathways.

IBD, liver disease, pancreatitis, GI malignancies, coeliac disease, and functional gut disorders with endoscopic and pharmacological management.

Stroke, epilepsy, MS, Parkinson's, headache syndromes, neuropathies, and neuromuscular conditions — high-yield for postgraduate exams.

Diabetes mellitus, thyroid disorders, adrenal pathology, pituitary disease, calcium metabolism, and reproductive endocrinology.

Acute kidney injury, CKD, glomerulonephritis, renal transplant, electrolyte disorders, and dialysis — essential renal medicine topics.

RA, SLE, vasculitis, crystal arthropathies, spondyloarthropathies, and connective tissue diseases with immunological investigations.

Anaemias, leukaemias, lymphomas, coagulopathies, thrombophilias, and transfusion medicine with laboratory interpretation.

Sepsis, pneumonia, meningitis, HIV, TB, hepatitis, STIs, and antimicrobial stewardship with UK resistance patterns.

Eczema, psoriasis, skin cancers, infections, blistering disorders, and drug reactions — clinical features and management.

Falls, delirium, dementia, polypharmacy, frailty, continence, and comprehensive geriatric assessment.

Acute abdomen, hernias, breast disease, vascular surgery, trauma, and perioperative care — key surgical principles.

Airway management, regional anaesthesia, pain medicine, critical care pharmacology, and perioperative assessment.

Trauma, resuscitation, toxicology, acute medical emergencies, and procedural skills for the emergency department.

Antenatal care, labour complications, gynaecological malignancies, fertility, contraception, and menstrual disorders.

Glaucoma, cataracts, retinal disease, acute red eye, visual loss, and ophthalmic emergencies.

Otitis media, hearing loss, tonsillitis, sinusitis, epistaxis, head and neck cancers, and airway emergencies.

Depression, anxiety, psychosis, bipolar disorder, eating disorders, personality disorders, and the Mental Health Act.

Chronic disease management, health screening, minor illness, contraception, and community-based medicine for primary care exams.

Symptom control, end-of-life care, communication skills, syringe drivers, and ethical frameworks in terminal illness.

Solid tumours, haematological malignancies, chemotherapy regimens, oncological emergencies, and palliative oncology.

Neonatal medicine, childhood infections, developmental milestones, safeguarding, congenital conditions, and paediatric emergencies.

Alcohol dependence, opioid substitution, withdrawal management, harm reduction, and dual diagnosis approaches.

Pharmacokinetics, adverse drug reactions, drug interactions, prescribing in special populations, and toxicology essentials.

Anatomy, physiology, biochemistry, genetics, immunology, and pathology foundations underpinning clinical medicine.

Epidemiology, biostatistics, screening programmes, health promotion, disease surveillance, and evidence-based medicine.

Consent, capacity, confidentiality, end-of-life decisions, resource allocation, and GMC Good Medical Practice.