Burns

Burns are tissue injuries caused by thermal, chemical, electrical, or radiation exposure. Assessment of burn depth and total body surface area (TBSA) guides fluid resuscitation and specialist referral.

MRCSPLAB 1UKMLA0 questions

Key Facts

Rule of Nines for TBSA estimation in adults: Head 9%, each arm 9%, anterior trunk 18%, posterior trunk 18%, each leg 18%, perineum 1% Lund and Browder chart: More accurate TBSA assessment; adjusts for age (especially children) Parkland formula: Fluid resuscitation — 4mL × body weight (kg) × %TBSA; half in first 8 hours, half in next 16 hours; use Hartmann's solution Referral to specialist burns centre (NICE): >10% TBSA (adults), >5% TBSA (children), full-thickness >5%, circumferential, airway/inhalation, chemical, electrical, special areas (face, hands, feet, genitalia, joints) Inhalation injury: Suspect if enclosed space fire, singed nasal hairs, carbonaceous sputum, hoarse voice, stridor — EARLY intubation Escharotomy: Required for circumferential full-thickness burns causing vascular or respiratory compromise Burn depth: Superficial (epidermis only, painful, erythema); partial thickness (dermal, blisters, painful); full thickness (painless, white/charred, no blanching) Toxic shock syndrome: Complication of burns (Group A Streptococcus or S. aureus toxin) — fever, rash, hypotension; manage with flucloxacillin + clindamycin

Overview

Key Facts

Burns management requires systematic assessment of depth, area, and associated injuries. Appropriate fluid resuscitation and timely referral to specialist services are critical.

Epidemiology

~175,000 burn injuries/year in UK (most minor). ~13,000 ED attendances for burns. ~4,500 hospital admissions. ~300 deaths annually. Peak populations: Children <5 (scalds) and young adult males (flame burns).

Aetiology

  • Thermal: Flame (~35%), scald (~30%), contact (~10%)
  • Chemical: Acid, alkali (alkali typically causes deeper injury — liquefactive necrosis)
  • Electrical: Low voltage (household), high voltage (>1000V — deep tissue injury, cardiac arrest risk)
  • Radiation: Sunburn, industrial
  • Non-accidental injury: Consider in children — symmetrical burns, clear demarcation, inconsistent history

Pathophysiology

Jackson's burn model (zones of injury):

  • Zone of coagulation: Central; irreversible tissue necrosis
  • Zone of stasis: Surrounding; potentially salvageable tissue (at risk of ischaemia in first 48 hours)
  • Zone of hyperaemia: Peripheral; will recover

Adequate resuscitation protects the zone of stasis from converting to necrosis.

Clinical Presentation

Burn Depth Assessment

DepthAppearanceSensationHealing
Superficial (epidermal)Red, dry, no blistersPainful7-10 days, no scarring
Superficial partialPink, moist, blisters, blanchesVery painful10-14 days, minimal scarring
Deep partialMottled pink/white, blisters, sluggish blanchReduced pain3-8 weeks, scarring likely
Full thicknessWhite, waxy, or charred; no blanchingPainlessDoes not heal spontaneously — needs grafting

Red Flags

  • Airway: Stridor, hoarseness, carbonaceous sputum, facial burns, singed nasal hairs → EARLY intubation (airway oedema progresses rapidly)
  • Circumferential burns: Limb — vascular compromise; chest — respiratory compromise → escharotomy
  • Electrical burns: May have minimal skin injury but deep tissue/organ damage; risk of cardiac arrhythmias, compartment syndrome, rhabdomyolysis
  • Non-accidental injury: Child with glove/stocking pattern burn, clear tide marks, inconsistent history

Differential Diagnosis

Burn TypeKey Management Point
ThermalCool with running water for 20 minutes
Chemical (acid)Copious water irrigation; do NOT neutralise
Chemical (alkali)Copious prolonged irrigation (causes deeper injury than acid)
Electrical (low voltage)ECG monitoring; assess entry/exit wounds
Electrical (high voltage)ICU; ECG, CK, rhabdomyolysis risk; deep tissue injury
RadiationUsually superficial; supportive care

Diagnosis / Investigation

Bedside

  • TBSA assessment: Rule of Nines (adults) or Lund and Browder chart (more accurate, especially children)
  • Patient's palm: ~1% TBSA (useful for small or scattered burns)
  • Airway assessment: Flexible nasendoscopy if inhalation injury suspected
  • ECG: Electrical burns (arrhythmia risk)

Bloods

  • FBC, U&Es, LFTs: Baseline
  • CK: Rhabdomyolysis (electrical burns, major burns)
  • ABG/VBG: CO level (carboxyhaemoglobin) if inhalation injury — co-oximetry
  • Lactate: Perfusion marker
  • G&S/crossmatch: Major burns
  • Clotting: DIC in severe burns

Imaging

  • CXR: Inhalation injury, ARDS
  • CT: If associated trauma

Management

Immediate (Pre-Hospital and ED)

  1. Safety: Remove from source of burn; stop the burning process
  2. Cool: Running tepid water for 20 minutes (effective up to 3 hours post-injury); avoid ice (causes vasoconstriction)
  3. Cover: Cling film (single layer, loosely) — reduces pain, prevents contamination
  4. ABCDE: Especially airway — intubate early if inhalation injury suspected
  5. 100% O₂: If CO poisoning suspected (SpO₂ unreliable — CO gives falsely normal SpO₂)

Fluid Resuscitation (Burns >15% TBSA adults, >10% children)

  • Parkland formula: 4mL × weight (kg) × %TBSA burns
  • Give 50% in first 8 hours from time of burn (NOT from time of arrival), remaining 50% over next 16 hours
  • Use Hartmann's solution (Ringer's lactate)
  • Titrate to urine output: Adults 0.5-1 mL/kg/hr; children 1 mL/kg/hr

Wound Management

  • Superficial: Simple dressings, analgesia
  • Partial thickness: Non-adherent dressings (e.g., Mepitel), silver-based antimicrobials if needed
  • Full thickness: Will require surgical debridement and skin grafting
  • Escharotomy: Circumferential full-thickness burns causing vascular/respiratory compromise

Referral to Burns Centre

  • 10% TBSA (adults), >5% (children), >5% (elderly >60)

  • Full-thickness burns >5%
  • Circumferential burns
  • Face, hands, feet, genitalia, perineum, major joints
  • Inhalation injury
  • Chemical or electrical burns
  • Non-accidental injury
  • Pre-existing medical conditions complicating management

Surgical

  • Debridement and grafting: Full-thickness and deep partial-thickness burns
  • Split-thickness skin graft (SSG): Most common; donor site (thigh) heals spontaneously
  • Negative pressure wound therapy: Aids graft take

Prognosis

  • Baux score: Mortality estimate = Age + %TBSA (modified Baux adds 17 for inhalation injury)
  • Minor burns (<10% TBSA, partial thickness): Excellent prognosis
  • Major burns (>40% TBSA): Significant mortality; modern burn centres have improved survival
  • Inhalation injury: Doubles mortality for any given TBSA
  • Hypertrophic scarring: Common in deep partial and full-thickness burns; managed with pressure garments, silicone, physiotherapy
  • Psychological morbidity: PTSD, depression, body image issues — psychological support essential

Other Relevant Information

Rule of Nines (Adults)

Body Part% TBSA
Head9%
Each arm9%
Anterior trunk18%
Posterior trunk18%
Each leg18%
Perineum1%

Parkland Formula

ParameterValue
Volume4mL × weight (kg) × %TBSA
First 8 hours50% of total
Next 16 hours50% of total
FluidHartmann's solution
Target UO0.5-1 mL/kg/hr (adult)